Simulations Plus, Inc. (Nasdaq: SLP), a leading provider of software and consulting services for pharmaceutical R&D and environmental toxicology, announced that it expects to file its annual report on Form 10-K, for the 2010 fiscal year ended August 31, 2010, with the Securities and Exchange Commission on Monday, November 29. Chairman and CEO Walt Woltosz will host a conference call to discuss the Company’s performance on Tuesday afternoon, November 30, at 1:15 p.m. PST / 4:15 p.m. EST.

The conference call will also be webcast live and may be accessed by first registering at the following website: https://www2.gotomeeting.com/register/831242179. Upon registering, you will receive a confirmation e-mail with a unique link and instructions for joining the call. Please dial in five to ten minutes prior to the scheduled start time. For listen-only mode, you may dial 916-233-3088, and enter access code 531-780-423.