Simulations Plus, Inc. (AMEX: SLP), a leading provider of ADMET absorption simulation and structure-to-property prediction software for pharmaceutical discovery and development, announced today that it has filed for an extension of the due date for its Form 10K-SB for the fiscal year ended August 31, 2005.

Ms. Momoko Beran, chief financial officer of Simulations Plus, said: “A number of accounting rule changes as well as schedule conflicts with our auditors and our internal staff have resulted in longer preparation time than we expected for the audit and write-up of the 10-KSB. We expect to release it not later than Friday, December 9. We’ll do our best to release it sooner, but we must have the proper reviews completed before release.”

Walt Woltosz, chairman and chief executive officer of Simulations Plus, added: “We will have a conference call on Tuesday, December 13, at 1:30 PM PST. This will give investors the weekend to read the 10-KSB before the call. We will also begin to provide guidance for the near future, especially for the current fiscal year, and to explain how our recent acquisitions and new product releases are combining to strengthen our offerings.”