Parameter Sensitivity Analysis in GastroPlus®

Authors: Lawless M
Keywords: absorption, bioavailability enhancement, GastroPlus tutorial video, parameter sensitivity analysis, salt formulations, solubility
Software: GastroPlus®
Division: PBPK

This video describes how to set up a parameter sensitivity analysis (PSA) in GastroPlus. This allows researchers to determine the effect of an input parameter, e.g., solubility, on a pharmacokinetic property like fraction absorbed. The tasks in Tutorial 5.3.7 will be illustrated.