Live Stream Learning with Simulations Plus Day Two

Live Stream Learning with Simulations Plus Day Two

Software: GastroPlus®
Division: PBPK

Bringing you scientific talks & poster presentations you missed from the 59th Annual SOT/Tox Expo and American Society for Clinical Pharmacology & Therapeutics conference by Simulations Plus… virtually.

Early assessment of PK properties with the ADMET Predictor® HTPK Simulation module, a high-throughput mechanistic PBPK approach

Early assessment of PK properties with the ADMET Predictor® HTPK Simulation module, a high-throughput mechanistic PBPK approach

Authors: Miller D, Jamois E
Software: ADMET Predictor®
Division: PBPK

This webinar introduces how the ADMET Predictor® HTPK Simulation module can effectively be used to provide early PK assessment in discovery programs.

Live Stream Learning with Simulations Plus: Day One

Live Stream Learning with Simulations Plus: Day One

Software: DILIsym®

Bringing you scientific talks & poster presentations you missed from the 59th Annual SOT/Tox Expo and American Society for Clinical Pharmacology & Therapeutics conference by Simulations Plus… virtually.

Physiologically-based pharmacokinetic models for children: Starting to reach maturation?

Physiologically-based pharmacokinetic models for children: Starting to reach maturation?

Publication: Pharmacol Ther
Software: GastroPlus®

Developmental changes in children can affect the disposition and clinical effects of a drug, indicating that scaling an...

Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer

Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer

Publication: Acta Pharmacol Sin
Software: ADMET Predictor®

Alflutinib (AST2818) is a third-generation epidermal growth factor receptor (EGFR) inhibitor that inhibits both EGFR-sensitive mutations and T790M mutations.