Predicting the effect of prandial stage and particle size on absorption of ODM-204

Predicting the effect of prandial stage and particle size on absorption of ODM-204

Publication: Eur J Pharm Biopharm
Software: GastroPlus®

The prediction of absorption properties plays a key role in formulation development when the compound under development shows poor solubility...

Tyrosol 1,2,3-triazole analogues as new acetylcholinesterase (AChE) inhibitors

Tyrosol 1,2,3-triazole analogues as new acetylcholinesterase (AChE) inhibitors

Publication: Comput Biol Chem
Software: ADMET Predictor®

The present work proposed the preparation of triazolic analogues of tyrosol, a biophenol found in olive oil and whose wide range of bioactivities...

DILIsym Simulations Support the Liver Safety of Ubrogepant in New Toxicological Sciences Publication

DILIsym Simulations Support the Liver Safety of Ubrogepant in New Toxicological Sciences Publication

Software: DILIsym®

Dr. Paul B. Watkins and Dr. Jeff Woodhead discuss the DILIsym analysis of the latest publication in Toxicological Sciences! Small-molecule calcitonin gene...

In Silico studies of novel Sildenafil self-emulsifying drug delivery system absorption improvement for pulmonary arterial hypertension

In Silico studies of novel Sildenafil self-emulsifying drug delivery system absorption improvement for pulmonary arterial hypertension

Publication: An Acad Bras Cienc
Software: GastroPlus®

Sildenafil is a potent selective inhibitor of phosphosdiesterase-5 previously used in erectile dysfunction and subsequently approved in 2005 for pulmonary...