Knowledge of the mode of action of an allelochemical can be valuable for several reasons, such as proving and...
Computational evaluation of endocrine activity of biocidal active substances
Exposure to endocrine disrupting chemicals is an important public health concern although only a few endocrine disruption chemicals have been identified so far.
AAPS VCU Chapter Webinar
GastroPlus applications to various drug delivery routes of administration.
Secure your 2021 Model Informed Drug Development (MIDD), PBPK or PBBM goals – Use your 2020 year-end budget today!
In 2021, we are committed to expanding our collaborations to advance the science of drug development, reduce the time and cost of research, and improve patient wellness. With this commitment, we are extending an exclusive offer for training and regulatory advice and support at 2020 rates for use next year.
Population pharmacokinetics of MYL-1401O (a trastuzumab biosimilar) and reference trastuzumab (Herceptin®) in patients with HER2-positive metastatic breast cancer
Mylan trastuzumab (MYL-1401O) is a biosimilar to trastuzumab (Herceptin®)
A Latent Variable Approach to Account for Correlated Inputs in Global Sensitivity
In pharmaceutical research and development decision-making related to drug candidate selection, efficacy and safety...
A latent variable approach to account for correlated inputs in global sensitivity analysis with cases from pharmacological systems modelling
In pharmaceutical research and development decision-making related to drug candidate selection...
DILI-sim Initiative
Consortium distributing and developing software for predicting and preventing drug-induced liver injury
DILIsym Services Presents Important DILIsym and NAFLDsym Software Applications at the Virtual AASLD Liver Meeting
2020 Virtual Liver Meeting Posters Showcase Customer Applications
6 Things You Need to Know about Diane Longo
Find out what inspires Diane Longo in her scientific research, proudest moments, and where Alec Baldwin fits in
BCS Class IV Oral Drugs and Absorption Windows: Regional-Dependent Intestinal Permeability of Furosemide
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet...
GastroPlus® Tutorial: Phase 2 Video 5 Population Simulation in GastroPlus
In this video we'll be talking about population simulations.
GastroPlus® Tutorial: Phase 2 Video 4 Solubility in GastroPlus
Learn how to integrate solubility in PBPK modeling software GastroPlus 9.7
GastroPlus® Tutorial: Phase 2 Video 3 ACAT™ model in GastroPlus
Learn how to use the Advanced Compartmental Absorption and Transit Model (ACAT) in GastroPlus 9.7
Simulations Plus Names Industry Veteran Will Frederick as Chief Financial Officer
Brings 25 years of Financial Leadership, Significant Public Company Experience, and M&A Expertise to Company
5-Fluorouracil Loaded Biogenic and Albumin Capped Gold Nanoparticles Using Bacterial Enzyme—In Vitro-In Silico Gastroplus® Simulation and Prediction
The study investigated in situ biosynthesis of albumin capped 5-fluorouracil (5-FU) loaded gold nanoparticles (NPs) using bacterial extract for enhanced...
Circulating tumor DNA analysis of metastatic renal cell carcinoma
The genomic landscape of metastatic renal cell carcinoma (RCC) is not well understood, and currently available data suggest that it is functionally distinct from that of localized...
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations
The purpose of this study is to show how the Ocular Compartmental Absorption & Transit (OCAT™) model in GastroPlus® can be used to characterize ocular...