In this video we'll be talking about compound multiple forms and solubility.
GPX™ Tutorial Series: ADMET Predictor® Import for GPX
In this video we'll be talking about ADMET Predictor® import for GPX.
GPX™ Tutorial Series: Physiologies and Physiology Schedules in GPX
In this video we'll be talking about physiologies and physiology schedules in GPX.
GPX™ Tutorial Series: Dosing Schedules
In this video we'll be talking about dosing schedules.
GPX™ Tutorial Series: Create a Project From Scratch
In this video we'll be talking about creating a project from scratch.
GPX™ Tutorial Series: Legacy Import
In this video we'll be talking about Legacy Import.
GPX™ Tutorial Series: Introduction to the GPX Paradigm
In this video we'll be talking about GPX Paradigm.
Simulations Plus Announces Extensions of U.S. FDA and NIEHS Research Collaborations
Extended projects support ongoing research into computational approaches and new approach methodologies for food and chemical safety assessment
What Scientists Paid Attention to in 2025: The 10 Most Read Blog Posts
Drug development is moving fast—and not everything deserves your attention.
Simulations Plus to Participate in Upcoming Investor Conferences
Simulations Plus, Inc. (Nasdaq: SLP) (“Simulations Plus”, “SLP”), a global leader in model-informed and AI-accelerated drug development that advances biopharma innovation, today announced that Shawn O’Connor, Chief Executive Officer, will be participating in the upcoming investor conferences...
10 Most Read Journal Articles of 2025
In drug development, the science never stands still. Constant research means there is constantly more to know and understand to stay current—but how can you filter through to what is most impactful?
Building Confidence in Physiologically BasedPharmacokinetic Modeling of CYP3A InductionMediated by Rifampin: An Industry Perspective
Physiologically- based pharmacokinetic (PBPK) modeling offers a viable approach to predict induction drug–druginteractions (DDIs) with the potential to streamline or reduce clinical trial burden if predictions can be made withsufficient confidence.
High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large In Vivo Pharmacokinetics Data Set
Accurate prediction of the pharmacokinetic (PK) properties of small-molecule drug candidates is a critical aspect of pharmaceutical research.
Design, Synthesis, and Pharmacological Evaluation of Metabolically Stable Apelin Receptor Antagonists with Improved In Vivo Exposure and Efficacy in Ovarian Cancer
The apelin receptor (APJ) has emerged as a potential novel therapeutic target in cancer due to its role in regulating cell proliferation, angiogenesis, and metastasis.
Investigating the SNAC-To-Drug Ratio for the Oral Absorption of Cyanocobalamin in Rats
The oral route of administration continues to be the preferred and most convenient method for drug delivery among both patients and healthcare professionals.
Novel Descriptors and Models for More Accurate ADME Predictions of Beyond Rule of Five Molecules
This study addresses the critical need for improved physicochemical descriptors and predictive models tailored to beyond Rule of Five (bRo5) compounds, including PROTACs and cyclic peptides. B
Development of a Pregnancy-Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin
Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders.
Clinical Pharmacology Considerations and Modeling of CAR-T Cell Therapies Using Monolix®
Chimeric antigen receptor T-cell (CAR-T) therapies have revolutionized the treatment of hematologic malignancies, delivering durable responses in patients with relapsed and refractory cancers.
Simulations Plus Highlights Platform Innovation and Strategic Direction at 2026 Investor Day
Showcases platform momentum, strategic priorities, and long-term value creation outlook