mlxDesignEval: A novel R package for design evaluation based on MonolixSuite, and its comparison to popED and PFIM

mlxDesignEval: A novel R package for design evaluation based on MonolixSuite, and its comparison to popED and PFIM

Conference: American Conference of Pharmacometrics
Software: Monolix®, Simulx®

Designing clinical trials to support population PK/PD modeling requires careful choices of sampling times, number of subjects, dose groups and other trial features to
ensure precise parameter estimation - with low relative standard errors [1].

Pharmacokinetic Studies and Synergistic Antitumor Effects of Cannabichromene and Cannabidiol in Drug-Resistant Breast Cancers

Pharmacokinetic Studies and Synergistic Antitumor Effects of Cannabichromene and Cannabidiol in Drug-Resistant Breast Cancers

Publication: Drug Delivery and Translational Research
Software: GastroPlus®

Triple-negative breast cancer (TNBC) is highly aggressive with limited treatment options, and resistance to doxorubicin (DOX) further compromises outcomes.