Exploring the Use of a Kinetic pH Calculation to Correct the ACAT Model with a Single Stomach Compartment Setting: Impact of Stomach Setting on Food Effect Prediction for Basic Compounds

Exploring the Use of a Kinetic pH Calculation to Correct the ACAT Model with a Single Stomach Compartment Setting: Impact of Stomach Setting on Food Effect Prediction for Basic Compounds

Publication: J Pharm Sci
Software: GastroPlus®

Advanced compartmental absorption and transit (ACAT) based computational models have become increasingly popular in the industry for predicting oral drug product...

Clinical Track: All-Presenter Panel Discussion

Clinical Track: All-Presenter Panel Discussion

Division: PBPK

Session panelists: Naveed Shaik, Gilead, Viera Lukacova, Dr. Rajanikanth Madabushi, U.S. FDA, Elizabeth Ludwig, Sandra Suarez-Sharp, Manuel Ibarra, University of the...