Simulations Plus

Improvements Provide New Capabilities Requested by User Community

Annual Revenues Up 23%, Net Earnings Up 158%

Conference Call to be on Thursday, November 9, at 4:15 PM EST

National Institute of Health Sciences is Equivalent to U.S. F.D.A.

Powerful Predictive Software Enhanced With Superior Molecular Modeling Capabilities

Company Underscores Guidance at Fiscal Year End

CEO to be Interviewed by the Wall Street Reporter

Board of Directors Approves Two-for-One Stock Split

Company Sets New Record for Third Quarter Revenues and Earnings

Company CEO to Present at Wall Street Reporter Small-Cap Discovery Conference

Company's Structure-Property Prediction and Model-Building Software Programs Will Be Sold as a Complete Structure-Property Prediction and Modeling Package

Large Pharmaceutical Company Renews Multi-year License

Important New Improvements Added to the Company's Gold Standard Software

Company Sets New Record for Second Quarter Revenues and Earnings

Conference Call to be on Thursday, April 13, at 4:15 PM EDT

Dramatic Improvements in Speed and Function Expected to Improve Drug Discovery

Large Customer Renews Annual Global License for GastoPlus ™