Proprietary Data Generated by Company Provides Unique Insight Needed By Drug Developers

Simulations Plus Announces Renewed Share Repurchase Program
Up to One Million Shares over 12 Months Authorized by Board of Directors

Simulations Plus Reports First Quarter FY2010 Financial Results
Record First Quarter Sees Pharmaceutical Software and Services Revenues Jump 21%, Consolidated Earnings Up 38% from 1QFY09

Simulations Plus Appoints John DiBella, M.S., Manager, Marketing and Sales
New Leadership Brings Strength in Science and Engineering

Simulations Plus Appoints Robert D. Clark, PH. D., Director of Life Sciences
Dr. Clark to Join Team in January

Simulations Plus Launches Abbreviate!™ for the iPhone™
New Software Speeds Up Typing on the PopularApple® iPhoneTM and iPod Touch®

Simulations Plus Reports FY2009 Financial Results
Sales up 2% to $9.143 Million, Cash up 26.9%, Earnings $0.08 Per Fully Diluted Share

Simulations Plus Sets Date for Fiscal Year 2009 Earnings Release and Conference Call
Conference Call to Be on Monday, November 30, at 4:15 PM EST

Simulations Plus Releases GastroPlus Version 6.1
Flagship Product Features New Routes of Administration & Numerous User Conveniences

Simulations Plus Releases ClassPharmer Version 4.7
Numerous Data Mining and Drug Design Capabilities Added

Simulations Plus Subsidiary Receives Medicare Accreditation
Highest level of accreditation achieved after on-site inspection

Simulations Plus CEO to Present at Southern California Investor Conference
Presentation to be Webcast

Simulations Plus Releases ADMET Predictor™ Version 4.0
Latest Update to Best-in-Class Software Further Extends Lead over Competition

Simulations Plus Reports Third Quarter FY2009 Financial Results
Best-in-Class Pharmaceutical Software & Services Sales Remain Strong

Simulations Plus Sets Date for Third Quarter Fiscal Year 2009 Earnings Release and Conference Call
Conference Call to Be on Thursday, July 16, at 4:15 PM EDT

Simulations Plus Reports Preliminary Results for Third Fiscal Quarter
Company CEO to Present at New York City Investor Meeting and Webinar