Simulations Plus

Conference Call to be on Wednesday, January 18, at 4:15 PM ET

Fiscal Year Pharmaceutical Software and Services Up 14.7%, EPS Up 29.3%

Conference Call to be on Thursday, December 1, 2011 at 4:30 PM EST

Prentke Romich Company to Acquire Subsidiary and Continue Operations

Company Uses Proprietary Software Tools to Design New Drug-like Molecules for Resistant Malaria Parasite

Pharmaceutical Software and Services Revenues Increase 6.9% for 4th Quarter, up 14.7% for the Fiscal Year

In-house Design Widens Eye Gaze Offerings and Substantially Increases Margins

Record Quarterly Revenue of $3.44 Million; Consolidated Earnings Up 42% and EPS Up 49% from 3QFY10

Growth Trend Continues with Another Record Quarter

Conference Call to Be on Monday, April 18, at 4:15 PM EDT

Adds New MedChem Designer Molecule Drawing, Expanded Graphics, and More

String of Record Quarters Sustains Multi-Year Growth Trend

New Predictions Further Extend Best-in-Class Software

Powerful Molecule Drawing Tool Added to World-Class Product Line

Center for Food Safety and Applied Nutrition (CFSAN) to Provide Data

Pharmaceutical Software and Services Revenues Up 18%, Words+ Subsidiary Up 8.3%, Consolidated Earnings Up 32%, and EPS Up 34% from 1QFY10

Conference Call to be on Friday, January 14, at 11:00 AM EST

Record First Quarter and Sustained Multi-year Growth Trend