We are pleased to offer PBPK models for large molecules (biologics)
GP IVIVCPlus™ Module Flyer
GastroPlus® PBPK & PBBM was the first software program to offer “mechanistic deconvolutions”.
GP Metabolism & Transporter Module Flyer
The Metabolism and Transporter Module in GastroPlus® calculates Michaelis-Menten rates for gut and liver (or any PBPK tissue) metabolism and for carrier-mediated transport (influx or efflux – again, for any tissue in a PBPK model) based on input values for Vmax and Km.
GP Optimization Module Flyer
The Optimization Module performs the multidimensional search needed to fit model parameters to one or more data sets automatically.
GP PBPKPlus™ Module Flyer
Ranked as the #1 PBPK software for In Vitro-In Vivo Extrapolation (IVIVE) & PBPK modeling by Pfizer!
GP PDPlus™ Module Flyer
Automated model selection – fit across all direct, indirect, phase-nonspecific cell killing, bacteria killing PD models with a single mouse click to extend your PBPK models in GastroPlus® and easily find relationships between the pharmacodynamics and pharmacokinetics of your compound using plasma and/or tissue concentration profiles!
AP Metabolism Module Flyer
Metabolism plays a critical role in the bioavailability of drugs, food additives, agrochemicals, and industrial chemicals.
AP High-throughput Pharmacokinetic (HTPK) Simulation Module Flyer
ADMET Predictor® property prediction and QSAR model-building application
AP AI-Driven Drug Design (AIDD) Module Flyer
Drug Design... Meet PBPK!
AP ADMET Modeler™ Module Flyer
ADMET Modeler is a QSAR/QSPR model building module in ADMET Predictor®.
AP Toxicity Module Flyer
Every early compound candidate screening tool should neglect toxicity aspects.
AP Physicochemical & Biopharmaceutical (PCB) Module Flyer
ADMET Predictor® property prediction and QSAR model-building application
AP MedChem Studio™ Module Flyer
MedChem Studio is now free of charge for all our users for extended data analysis capabilities.
QSP Ulcerative Colitis (UC) Model Flyer
Quantitative Systems Pharmacology (QSP)
Ulcerative Colitis Model
QSP Systemic Lupus Erythematosus (SLE) Model Flyer
Quantitative Systems Pharmacology (QSP)
Systemic Lupus Erythematosus Model
QSP Rheumatoid Arthritis (RA) Model Flyer
Quantitative Systems Pharmacology (QSP)
Rheumatoid Arthritis Model
QSP Psoriatic Arthritis Model Flyer
Quantitative Systems Pharmacology (QSP)
Psoriatic Arthritis Model
QSP Psoriasis Model Flyer
Quantitative Systems Pharmacology (QSP)
Psoriasis Model
QSP Crohn’s Disease (CD) Model Flyer
Quantitative Systems Pharmacology (QSP)
Crohn’s Disease (CD) Model
QSP Atopic dermatitis Model Flyer
Quantitative Systems Pharmacology (QSP)
Atopic dermatitis Model