Simulations Plus

Deficiency or dysfunction in regulatory factors that control the complement cascade critically contribute to several rare diseases...

GastroPlus® Monthly Newsletter 2024

As a nutritional biochemist by training, I am really excited about the effectiveness of current treatments for obese patients—and it extends well beyond weight loss. 

Quantitative systems pharmacology (QSP) is gaining acceptance and utilization in many drug development programs, but even those who appreciate its value may not fully recognize the extent to which it has already achieved impact and/or its range of potential applications.

International Perspectives on Model-Informed Precision Dosing

GastroPlus® Monthly Newsletter 2024

According to an article published by United Nations News last year, women in STEM are still not the norm. Only one in three researchers worldwide is female.

GastroPlus® Newsletter February 2024

Unlocking the Power of PBPK Modeling

If a new drug candidate behaves unexpectedly when dosed to animals or humans, it’s likely to delay or even terminate the drug’s development.

GastroPlus® Newsletter January 2024

10 Most Read Journal Articles of 2023

In our industry, new research is constantly evolving our most current knowledge—and it’s critical to stay up-to-date with the latest advancements and best practices.

GastroPlus® Newsletter December 2023

In the highly regulated world of clinical research, compliance is an ongoing concern, but can be viewed as an annoying and costly item to check off a regulatory to-do list.

Fully Power Your First-in-Human Predictions

Determining appropriate dosage for your first in human (FIH) clinical trials is critical.

GastroPlus® Newsletter November 2023

Are your clinical trials showing potential liver toxicity?

There are many different things that make a model "good."