Simulations Plus

One of the significant challenges faced by pharmaceutical companies is the sometimes unclear guidance on what data regulators want to see included in their submissions and the format in which it should be provided.

Physiologically-based pharmacokinetic (PBPK) modeling is now a standard tool used across the pharmaceutical industry to increase understanding of a drug’s behavior in the body and to help guide its development.

The first algorithm ever developed for processing by machine was designed by Ada Lovelace, a pioneering mathematician in the 19th century.

Patient trust is critical to ensuring adequate enrollment and retention of clinical trial participants.

In a world where only 30% of researchers are female, it’s critical to highlight the women who have built their careers in STEM and share their insights and advice with others.

How to Use Your Predictions to Support Regulatory Submission

Dr. Camila de Almeida, Director of Clinical Pharmacology at Simulations Plus, shares her proudest accomplishments, career trajectory, and words of advice for future women in science.

Deficiency or dysfunction in regulatory factors that control the complement cascade critically contribute to several rare diseases...

GastroPlus® Monthly Newsletter 2024

As a nutritional biochemist by training, I am really excited about the effectiveness of current treatments for obese patients—and it extends well beyond weight loss. 

Quantitative systems pharmacology (QSP) is gaining acceptance and utilization in many drug development programs, but even those who appreciate its value may not fully recognize the extent to which it has already achieved impact and/or its range of potential applications.

International Perspectives on Model-Informed Precision Dosing

GastroPlus® Monthly Newsletter 2024

According to an article published by United Nations News last year, women in STEM are still not the norm. Only one in three researchers worldwide is female.

GastroPlus® Newsletter February 2024

Unlocking the Power of PBPK Modeling

If a new drug candidate behaves unexpectedly when dosed to animals or humans, it’s likely to delay or even terminate the drug’s development.

GastroPlus® Newsletter January 2024

10 Most Read Journal Articles of 2023

In our industry, new research is constantly evolving our most current knowledge—and it’s critical to stay up-to-date with the latest advancements and best practices.