- Webinars
Key Applications for Quantitative Systems Pharmacology Across the Drug R&D Continuum
-
-
9:00 am PDT
-
Online
This ASCPT webinar is Part 2 of 4 in the Systems Pharmacology Educational Webinar Series. This session will provide a collection of case studies to exemplify the application of quantitative systems pharmacology (QSP) to address model-informed drug development (MIDD) questions across the whole spectrum from discovery to recovery including both efficacy and toxicity.
Topics will include:
- Application of a QSP model of IBD to prioritize combination therapies
- Application of QSP modeling in reverse translation
- Leveraging the QSP model to support clinical development of T-Cell engaging Bispecifics
- Phase 2 simulations intended to obviate clinical studies needed to address US Food and Drug Administrations Fixed Combination Rule
Learning Objectives: Understand the breadth of applications of QSP in end-to-end drug development. Highlight applications of mechanistic modeling to accelerate drug discovery and development. Unveil the use of mechanistic modeling to enhance preclinical translatability and decision making.
PANELISTS:
- Dominic Whittaker, Ph.D.
- Kapil Gadkar, Ph.D.
- Pegy Foteinou, Ph.D.
- Scott Siler, Ph.D.
- Valerie Damian, Ph.D.