At Simulations Plus, we strive to improve the productivity of science-based research and development through the use of our technology. We realize, however, that this is something we cannot do alone, and we actively collaborate with a variety of universities, contract research organizations (CROs), distributors, and government agencies to help meet our (and their) client’s goals. Below is a partial list of the partnerships we have formed to continue advancing the use of modeling & simulation approaches.
Interested in Collaboration?
Interested in working with us and/or utilizing our technology to support clients? Let’s connect!
-
Academic Collaborators
We are always interested in speaking with professors & students on ways in which we can support academic research and coursework:
The University of Buffalo, UB Center of Excellence in Pharmacokinetics and Pharmacodynamics
-
CRO & CDMO Partners
The demand for machine learning, PBBM, and PBPK modeling support continues to grow, and we encourage CROs and CDMOs to explore incorporating our software to assist with their client projects:
Admescope: Oulu, FinlandCatalent: Somerset, NJ, USA
Crystal Pharmatech: Cranbury, NJ, USA
Cyprotex: Macclesfield, United Kingdom
Evotec: Hamburg, Germany
LabCorp: Madison, WI, USA
Leadingpharm: Beijing, China
Lonza: Basel, Switzerland
PAREXEL: Uxbridge, United Kingdom
PharmaDirections: Cary, NC, USA
Pharmaron: Waltham, MA, USA
PhinC Development: Massy, France
Quotient Sciences: Nottingham, United Kingdom
Scantox: Lille Skensved, Denmark
Solvo Biotechnology: Budapest, Hungary
Sygnature Discovery: Nottingham, United Kingdom
Thermo Fisher: Waltham, MA, USA
WuXi Apptec: Shanghai, China
3D BioOptima: Suzhou, China
-
Distributors
We have strong distributor channels in Brazil, China, India, Japan, and South Korea that provide local technical & marketing support for us, and we are always on the lookout to establish similar relationships in other territories. View our DPA for distributors here.
Electrolab India Pvt. Ltd.: Mumbai, India
Molecular Solutions: Bangalore, India
Northern Science Consulting: Hokkaido, Japan
PharmoGo Co. Ltd.: Shanghai, China
Quantum Bio Solutions: South Korea
ICF: Brazil
-
Government Collaborations
Much of the momentum behind the increased use of PBPK modeling has been driven by regulatory agencies around the world, who all have access to our software, and we are happy to partner with several of them on different projects:
National Toxicology Program: We have been collaborating with scientists from the U.S. EPA/NIEHS/NTP for several years on the use of GastroPlus® and ADMET Predictor® to efficiently screen the Tox21 library – more details can be found here:- Simulations Plus Extends Research Agreement with National Institute of Environmental Health Sciences
- U.S. Environmental Protection Agency Purchases Multiple Licenses of Simulations Plus Software
U.S. FDA: We currently have 9 funded grant awards from the FDA to continue to enhance the GastroPlus platform, and most divisions have access to the software – read about some of these grants here:
- Simulations Plus and the University of Bath Awarded New FDA Grant
- Simulations Plus Embarks on Collaboration with Northeastern University and The TIM Company Through New FDA Grant
National Institutes of Health: We are thankful the NIH supports our mission to help modernize drug development and reduce the time and costs associated with developing new therapies. Building on our expertise in drug-induced liver injury and nonalcoholic fatty liver disease, RENAsym® will expand our Quantitative Systems Pharmacology (QSP) offerings to include potential damage to the kidney. More details can be found here:
- Simulations Plus Subsidiary DILIsym Awarded Grant for up to $1.7 Million For Model Development
- DILIsym Services was awarded a Phase II $1.5M NIH SBIR grant to continue development of RENAsym, software for predicting drug-induced kidney injury
- Policy on Disclosure and Management of Financial Conflicts of Interest related to Public Health Service Research
- CDC
- EMA
- Health Canada
- NMPA
- PMDA
- US EPA
- US Army
- Walter Reed Army Institute of Research
-
Consortiums & Associations
Cosmetics Europe