Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach

Authors: Lignet F, Sherbetijan E, Kratochwil N, Jones RN, Suenderhauf C, Otteneder MB, Singer T, Parrott N
Publication: Pharm Res
Keywords: in silico, metabolism, minipig, pharmacokinetics
Software: ADMET Predictor®

Purpose

This study aims to expand our understanding of the mechanisms of drug absorption, distribution, metabolism and excretion in the Göttingen minipig to aid a knowledge-driven selection of the optimal species for preclinical pharmaceutical research.