Patient-Centric Design of Long-Acting Injectable Drug Products

Authors: Lukacova V
Conference: AAPS
Keywords: drug products, in vivo dissolution, long-acting injectable formulations, PBPK model
Division: PBPK

Outline

  • PBPK model description
  • Exploring mechanisms affecting in vivo dissolution of low-solubility compound crystalline suspensions
    • Effect of inflammation
    • Example Paliperidone Palmitat
    • Effect of dissolution rate –Example Cabotegravir
  • Putting it all together

By Viera Lukacova

Presented at AAPS “Patient-Centric Design of Long-Acting Injectable Drug Products” Workshop Virtual Event March 9-10, 2022