An Update to the DILI-sim Initiative and the DILIsym Tool

Authors: Howell BA
Conference: PBSS
Keywords: DILI-sim Initiative, drug dosage, drug-induced liver injury, liver safety
Software: DILIsym®
Division: Quantitative Systems Pharmacology (QSP)

Talk Summary

  • DILIsym is a modeling and simulation tool used for predicting and understanding drug-induced liver injury
  • Tools like DILIsym can be used for finding the right dose with respect to safety liabilities; this is already happening in many cases