Simulations Plus, Inc. (NASDAQ: SLP), the premier provider of simulation and modeling software and consulting services for all phases of pharmaceutical/chemical research and development, announced today that it has extended the Material Transfer Agreement (MTA) with the Division of the National Toxicology Program (DNTP) of the U.S. National Institute of Environmental Health Sciences (NIEHS) for an additional three year term. Simulations Plus will continue to provide licenses for its GastroPlus™, ADMET Predictor™, and MedChem Studio™ software programs for use by the DNTP/NIEHS. The DNTP within the NIEHS is conducting research along with several agencies, including the U.S. Environmental Protection Agency, the U.S. Army, the National Human Genome Institute, and the Centers for Disease Control in the National Toxicology Project.

John DiBella, vice president of marketing and sales for Simulations Plus, said: “We are pleased to continue supporting the research efforts at the DNTP through our modeling & simulation technology. Over the initial two-year term, scientists at the DNTP were impressed with the accuracy of our predictive models and the intuitive way they operated, and they shared their experiences with others by presenting at conferences and webinars. In this next phase of the collaboration, they are interested in exploring the use of physiologically based pharmacokinetic (PBPK) modeling through GastroPlus and to leverage the predictions of concentrations in various tissues to continue prioritizing the many tens of thousands of potentially toxic compounds for testing. Through their feedback, we expect to refine our tools to help with the continued expansion into new markets focused on toxicology research, including industrial chemicals, agrochemicals, and consumer goods companies. To date, our sales efforts have resulted in recent software license orders to several companies and leading research organizations in these sectors.”