Simulations Plus

ADMET Predictor is the flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, and AI-driven drug design.

DILIsym is Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide an indication of the potential drug-induced liver injury (DILI) hazard posed by individual molecules and/or to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.

Built for model-informed drug development computing, MonolixSuite is a fast, easy-to-use, and powerful suite of applications for pharmacometrics analysis, modeling, and simulation.

NAFLDsym modeling software is a mechanistic, mathematical model of nonalcoholic fatty liver disease (NAFLD), which can be used to predict efficacy for treatment modalities developed for NAFLD and nonalcoholic steatohepatitis (NASH).

DDDPlus is the industry’s leading mechanistic in vitro dissolution software for formulation and analytical scientists.

MembranePlus is the industry’s leading mechanistic in vitro permeability & hepatocyte modeling software for IVIVE of absorption and systemic clearance/distribution processes.

OBESITYsym runs on the Thales QSP modeling platform, which allows you to generate validated, diverse simulation populations with a distribution of responses identical to clinical data-including temporal treatment and placebo responses.

The ILDsym QSP modeling software is a mechanistic, mathematical model of interstitial lung disease (ILD) associated with systemic sclerosis (SSc). ILDsym can be used to predict efficacy for treatment modalities developed for SSc-ILD (and other interstitial lung diseases with custom modifications and additions).

The IPFsym® QSP modeling software is a mechanistic, mathematical model of idiopathic pulmonary fibrosis (IPF). IPFsym can be used to predict efficacy for treatment modalities developed for IPF (and other lung diseases with custom modifications and additions).

RENAsym is quantitative systems toxicology (QST) software for predicting and understand drug-induced kidney injury with the use of mechanistic, mathematical modeling to predict whether new drug candidates will cause renal injury signals in patients and to enhance the understanding of mechanisms that contribute to renal safety signals already observed in the clinic.

MedChem Designer is a tool that combines innovative molecule drawing features with fast and accurate ADMET property predictions from our top-ranked ADMET Predictor.